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[(2R,3S,4R,5R)-4-(acetylamino)-3,5-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate

Q8N6T7 — NAD-dependent protein deacylase sirtuin-6

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand A2N

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand A2N

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q8N6T7n/a3pkjA2NA1000e3pkjA2Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q8N6T7n/a3pkjA2NB1000e3pkjB2Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q8N6T7n/a3pkjA2NB1000e3pkjE2Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q8N6T7n/a3pkjA2NC1000e3pkjC1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q8N6T7n/a3pkjA2ND1000e3pkjD2Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q8N6T7n/a3pkjA2NE1000e3pkjB2Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q8N6T7n/a3pkjA2NE1000e3pkjE2Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q8N6T7n/a3pkjA2NF1000e3pkjF2Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2