2-OXOGLUTARIC ACID

Q9C0B1 — Alpha-ketoglutarate-dependent dioxygenase FTO -)-demethylase FTO) -methyladenosine-demethylase FTO) -)-demethylase FTO) -demethylase FTO) -methyladenosine demethylase FTO

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB08845

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB08845

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q9C0B1	DB08845	4zs2	AKG	A	601	e4zs2A1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	FTO_NTD
Q9C0B1	DB08845	4zs2	AKG	A	601	e4zs2A2	STAT-like	Alpha-ketoglutarate-dependent dioxygenase FTO helical domain	Alpha-ketoglutarate-dependent dioxygenase FTO helical domain	FTO_CTD
Q9C0B1	DB08845	4zs3	AKG	A	601	e4zs3A1	STAT-like	Alpha-ketoglutarate-dependent dioxygenase FTO helical domain	Alpha-ketoglutarate-dependent dioxygenase FTO helical domain	FTO_CTD
Q9C0B1	DB08845	4zs3	AKG	A	601	e4zs3A2	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	FTO_NTD
Q9C0B1	DB08845	5dab	AKG	A	611	e5dabA2	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	FTO_NTD
Q9C0B1	DB08845	5dab	AKG	A	611	e5dabA3	STAT-like	Alpha-ketoglutarate-dependent dioxygenase FTO helical domain	Alpha-ketoglutarate-dependent dioxygenase FTO helical domain	FTO_CTD
Q9C0B1	DB08845	5f8p	AKG	A	603	e5f8pA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	FTO_NTD
Q9C0B1	DB08845	5f8p	AKG	A	603	e5f8pA2	STAT-like	Alpha-ketoglutarate-dependent dioxygenase FTO helical domain	Alpha-ketoglutarate-dependent dioxygenase FTO helical domain	FTO_CTD
Q9C0B1	DB08845	6akw	AKG	A	601	e6akwA1	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	FTO_NTD
Q9C0B1	DB08845	6akw	AKG	A	601	e6akwA2	STAT-like	Alpha-ketoglutarate-dependent dioxygenase FTO helical domain	Alpha-ketoglutarate-dependent dioxygenase FTO helical domain	FTO_CTD
Q9C0B1	DB08845	7wcv	AKG	A	601	e7wcvA1	STAT-like	Alpha-ketoglutarate-dependent dioxygenase FTO helical domain	Alpha-ketoglutarate-dependent dioxygenase FTO helical domain	FTO_CTD
Q9C0B1	DB08845	7wcv	AKG	A	601	e7wcvA2	jelly-roll	Double-stranded beta-helix	Double-stranded beta-helix	FTO_NTD