[[(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate

Q9Y3Z3 — Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand CZF

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand CZF

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q9Y3Z3	n/a	6tx0	CZF	A	706	e6tx0A1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6tx0	CZF	A	706	e6tx0B1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6tx0	CZF	B	707	e6tx0A1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6tx0	CZF	B	707	e6tx0B1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	A	706	e6txaA1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	A	706	e6txaB1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	A	706	e6txaC1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	B	706	e6txaA1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	B	706	e6txaB1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	B	706	e6txaD1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	C	709	e6txaB1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	C	709	e6txaC1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	C	709	e6txaD1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	E	706	e6txaE1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	E	706	e6txaF1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	E	706	e6txaG1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	F	706	e6txaE1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	F	706	e6txaF1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	F	706	e6txaH1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	G	707	e6txaE1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	G	707	e6txaG1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	G	707	e6txaH1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	H	707	e6txaF1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	H	707	e6txaG1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	H	707	e6txaH1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	J	707	e6txaI1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	J	707	e6txaJ1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	J	707	e6txaL1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	K	707	e6txaI1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	K	707	e6txaK1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	K	707	e6txaL1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	L	706	e6txaJ1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	L	706	e6txaK1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	L	706	e6txaL1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	M	706	e6txaM1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	M	706	e6txaN1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	M	706	e6txaO1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	N	706	e6txaM1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	N	706	e6txaN1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	N	706	e6txaP1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	O	707	e6txaM1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	O	707	e6txaO1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	O	707	e6txaP1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	P	707	e6txaN1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	P	707	e6txaO1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txa	CZF	P	707	e6txaP1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txf	CZF	A	706	e6txfA1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txf	CZF	A	706	e6txfB1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txf	CZF	B	707	e6txfA1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6txf	CZF	B	707	e6txfB1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6yom	CZF	A	706	e6yomA1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6yom	CZF	A	706	e6yomB1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6yom	CZF	B	707	e6yomA1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD
Q9Y3Z3	n/a	6yom	CZF	B	707	e6yomB1	PDEase-like	HD-domain/PDEase-like	HD-domain/PDEase-like	HD