DrugDomain logoDrugDomain

(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB01095

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB01095

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P04035DB010951hwi115A2e1hwiA1Alpha-beta plaitsHMG-CoA reductaseNAD-binding domain of HMG-CoA reductaseHMG-CoA_red
P04035DB010951hwi115A2e1hwiA2Alpha-beta plaitsHMG-CoA reductaseSubstrate-binding domain of HMG-CoA reductaseHMG-CoA_red
P04035DB010951hwi115A2e1hwiB2Alpha-beta plaitsHMG-CoA reductaseSubstrate-binding domain of HMG-CoA reductaseHMG-CoA_red
P04035DB010951hwi115B1e1hwiA2Alpha-beta plaitsHMG-CoA reductaseSubstrate-binding domain of HMG-CoA reductaseHMG-CoA_red
P04035DB010951hwi115B1e1hwiB1Alpha-beta plaitsHMG-CoA reductaseNAD-binding domain of HMG-CoA reductaseHMG-CoA_red
P04035DB010951hwi115B1e1hwiB2Alpha-beta plaitsHMG-CoA reductaseSubstrate-binding domain of HMG-CoA reductaseHMG-CoA_red
P04035DB010951hwi115C4e1hwiC1Alpha-beta plaitsHMG-CoA reductaseNAD-binding domain of HMG-CoA reductaseHMG-CoA_red
P04035DB010951hwi115C4e1hwiC2Alpha-beta plaitsHMG-CoA reductaseSubstrate-binding domain of HMG-CoA reductaseHMG-CoA_red
P04035DB010951hwi115C4e1hwiD2Alpha-beta plaitsHMG-CoA reductaseSubstrate-binding domain of HMG-CoA reductaseHMG-CoA_red
P04035DB010951hwi115D3e1hwiC2Alpha-beta plaitsHMG-CoA reductaseSubstrate-binding domain of HMG-CoA reductaseHMG-CoA_red
P04035DB010951hwi115D3e1hwiD1Alpha-beta plaitsHMG-CoA reductaseNAD-binding domain of HMG-CoA reductaseHMG-CoA_red
P04035DB010951hwi115D3e1hwiD2Alpha-beta plaitsHMG-CoA reductaseSubstrate-binding domain of HMG-CoA reductaseHMG-CoA_red