NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

P04035 — 3-hydroxy-3-methylglutaryl-coenzyme A reductase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB03461

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB03461

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P04035	DB03461	1dqa	NAP	A	1	e1dqaA1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB03461	1dqa	NAP	A	1	e1dqaA2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB03461	1dqa	NAP	A	1	e1dqaB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB03461	1dqa	NAP	B	2	e1dqaA1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB03461	1dqa	NAP	B	2	e1dqaA2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB03461	1dqa	NAP	B	2	e1dqaB1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB03461	1dqa	NAP	B	2	e1dqaB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB03461	1dqa	NAP	C	3	e1dqaC1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB03461	1dqa	NAP	C	3	e1dqaC2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB03461	1dqa	NAP	C	3	e1dqaD2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB03461	1dqa	NAP	D	4	e1dqaC2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB03461	1dqa	NAP	D	4	e1dqaD1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB03461	1dqa	NAP	D	4	e1dqaD2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red